Serie A · former league club
- Fiorentina 92 shared
- Inter 91 shared
- Milan 85 shared
- Napoli 69 shared
- Roma 68 shared
- Juventus 67 shared
- Lazio 50 shared
- Chelsea 8 shared
- Monaco 7 shared
- Atlético Madrid 6 shared
- Sevilla 6 shared
- Real Madrid 6 shared
- Manchester United 6 shared
- Valencia 6 shared
- Barcelona 5 shared
- Southampton 5 shared
- Marseille 5 shared
- West Ham United 5 shared
- Leicester City 5 shared
- Arsenal 4 shared
- Tottenham Hotspur 4 shared
- Paris Saint-Germain 4 shared
- Crystal Palace 4 shared
- Torino 85 shared
- Parma 80 shared
- Bologna 78 shared
- Brescia 75 shared
- Atalanta 68 shared
- Genoa 61 shared
- Hellas Verona 60 shared
- Empoli 60 shared
- Lecce 57 shared
- Palermo 52 shared
- Udinese 50 shared
- Cremonese 49 shared
- SPAL 49 shared
- Monza 49 shared
- Cagliari 47 shared
- Livorno 45 shared
- Pescara 45 shared
- Como 43 shared
- Cesena 43 shared
- Catania 42 shared
- Spezia 41 shared
- Venezia 40 shared
- Siena 39 shared
- Salernitana 36 shared
- Chievo 31 shared
- Pisa 30 shared
- Crotone 21 shared
- Sassuolo 20 shared
- Benevento 16 shared
- Frosinone 13 shared
- Mallorca 8 shared
- Sporting CP 7 shared
- Carpi 7 shared
- Middlesbrough 6 shared
- Fatih Karagümrük 6 shared
- Hamburger SV 5 shared
- Panathinaikos 5 shared
- Rennes 5 shared
- Nottingham Forest 5 shared
- AEK 5 shared
- Levante 5 shared
- Stuttgart 4 shared
- Rangers 4 shared
- Sunderland 4 shared
- Benfica 4 shared
- PSV 4 shared
- Olympiakos 4 shared
- Lens 4 shared
- Celta Vigo 4 shared
- Watford 4 shared
- QPR 4 shared
- Granada 4 shared
Famous players who played for Sampdoria
- Bruno Fernandes 2016–2017, 2017
- Shkodran Mustafi 2012–2014
- Maya Yoshida 2020, 2020–2022
- Sergio Romero 2011–2015
- Mauro Icardi 2011–2013
- Samuel Eto'o 2015
- Ruud Gullit 1993–1994, 1994–1995
- Roberto Mancini 1982–1997
- Jürgen Klinsmann 1997–1998
- Clarence Seedorf 1995–1996
- Luis Muriel 2015, 2015–2017
- Lucas Torreira 2015–2018
- Antonio Cassano 2007–2008, 2008–2011, 2015–2017
- Antonio Candreva 2020–2021, 2021–2023
- Fabio Quagliarella 2006–2007, 2016–2023
- Ivan Strinić 2017–2018
- Patrik Schick 2016–2017
- Siniša Mihajlović 1994–1998
- Vincenzo Montella 1996–1999, 2007–2008
- Juan Sebastián Verón 1996–1998
- Luis Suárez 1970–1973
- Lorenzo Insigne 2026–
- Gianluca Vialli 1984–1992
- Christian Karembeu 1995–1997
- Ante Budimir 2016–2018
- Enzo Maresca 2012–2014
- Birkir Bjarnason 2013–2014
- Sebastian Giovinco 2022
- Alessio Romagnoli 2014–2015
- Jesé 2023
- Milan Škriniar 2016–2017
- M'Baye Niang 2025
- Gianluca Pagliuca 1987–1994
- Paulo Silas 1991–1992
- Simone Zaza 2010–2013
- Simone Inzaghi 2005
- Toninho Cerezo 1986–1992
- Marco Borriello 2005–2006
- Graziano Pellè 2012
- Walter Zenga 1994–1996
Source: Wikidata (CC0), Wikipedia club articles and player infoboxes (years at each club). Youth spells and appearances that look unplayed are left out; volunteer-kept records can contain gaps or errors.