Serie A · former league club
- Inter 46 shared
- Fiorentina 43 shared
- Juventus 37 shared
- Milan 36 shared
- Napoli 36 shared
- Roma 25 shared
- Lazio 25 shared
- Genoa 78 shared
- Livorno 62 shared
- Torino 59 shared
- Empoli 53 shared
- Atalanta 53 shared
- Cesena 53 shared
- Parma 48 shared
- Cremonese 46 shared
- Venezia 45 shared
- Pisa 45 shared
- SPAL 43 shared
- Sampdoria 41 shared
- Brescia 40 shared
- Hellas Verona 40 shared
- Catania 37 shared
- Monza 37 shared
- Pescara 37 shared
- Siena 36 shared
- Cagliari 36 shared
- Salernitana 34 shared
- Lecce 33 shared
- Bologna 32 shared
- Como 32 shared
- Crotone 31 shared
- Palermo 30 shared
- Frosinone 27 shared
- Benevento 18 shared
- Chievo 17 shared
- Sassuolo 17 shared
- Udinese 16 shared
- Carpi 16 shared
- Sporting CP 4 shared
Famous players who played for Spezia
- Alberto Gilardino 2017–2018
- Goran Pandev 2002–2003
- Luciano Spalletti 1986–1990
- Cristian Zaccardo 2000–2001
- Jakub Kiwior 2021–2023
- Albin Ekdal 2022–2023
- Federico Marchetti 2023
- Eldor Shomurodov 2023
- Ethan Ampadu 2022–2023
- Matteo Pessina 2017–2018
- Mário Rui 2012–2013
- Hördur Magnússon 2013–2014
- Roberto Gagliardini 2014–2015
- Enrico Albertosi 1957–1958
- Mislav Oršić 2013–2014
- Martin Erlić 2018–2022
- Daniel Maldini 2022–2023
- Viktor Kovalenko 2021–2022, 2022–2023
- Alen Stevanović 2015
- Umar Sadiq 2014–2016
- Rey Manaj 2021–2022
- Riccardo Saponara 2021
- Mattia Caldara 2022–2023
- Raffaele Palladino 2018
- Sergio Bertoni 1949–1950
- Jeroen Zoet 2020–2024
- Gianluca Lapadula 2025–2026
- Stefan Ristovski 2015
- Simon Sluga 2015–2016
- Stefano Okaka 2012–2013
- Nicola Leali 2013–2014
- Bartłomiej Drągowski 2022–2024
- Szymon Żurkowski 2023, 2023–2026
- Simone Scuffet 2019–2020
- Dorin Goian 2012–2013
- Mario Genta —
- Pio Esposito 2024
- Cristiano Piccini 2012–2013
- Antonio Luna 2015
- David Strelec 2021–2024
Source: Wikidata (CC0), Wikipedia club articles and player infoboxes (years at each club). Youth spells and appearances that look unplayed are left out; volunteer-kept records can contain gaps or errors.