Serie A
- Inter 26 shared
- Roma 21 shared
- Fiorentina 21 shared
- Napoli 18 shared
- Juventus 13 shared
- Milan 12 shared
- Lazio 11 shared
- Marseille 7 shared
- Hellas Verona 32 shared
- Bologna 31 shared
- Parma 27 shared
- Cagliari 26 shared
- Frosinone 25 shared
- Genoa 24 shared
- Monza 23 shared
- Atalanta 22 shared
- Torino 21 shared
- Empoli 21 shared
- Sampdoria 20 shared
- Cesena 18 shared
- Cremonese 17 shared
- SPAL 17 shared
- Spezia 17 shared
- Chievo 16 shared
- Lecce 16 shared
- Catania 15 shared
- Brescia 13 shared
- Salernitana 13 shared
- Pescara 13 shared
- Benevento 13 shared
- Como 12 shared
- Venezia 11 shared
- Livorno 11 shared
- Pisa 11 shared
- Palermo 10 shared
- Siena 10 shared
- Carpi 10 shared
- Crotone 9 shared
- Udinese 7 shared
- Rennes 5 shared
- Las Palmas 4 shared
Famous players who played for Sassuolo
- Kevin-Prince Boateng 2018–2019
- Alberto Aquilani 2017
- Nemanja Matić 2025–
- Manuel Locatelli 2018–2019, 2019–2023
- Šime Vrsaljko 2014–2016
- Merih Demiral 2019
- Simone Zaza 2013–2015
- Francesco Acerbi 2013–2018
- Vlad Chiricheș 2019–2020, 2020–2022
- Gianluca Scamacca 2017–2022
- Alessandro Matri 2016–2020
- Matteo Politano 2015–2019
- Lorenzo Pellegrini 2015–2017
- Duje Ćaleta-Car 2026–
- Stefano Sensi 2016–2020
- Giacomo Raspadori 2019–2023
- Davide Frattesi 2017–2024
- Filip Djuricic 2018–2022
- Kaan Ayhan 2020–2023
- Mert Müldür 2019–2023
- Samu Castillejo 2023–2024
- Reto Ziegler 2013–2014
- Paolo Cannavaro 2014, 2014–2017
- Arijanet Muric 2025–2026, 2026–
- Antonio Sanabria 2014
- Matías Viña 2023–2024
- Martin Erlić 2022–2024
- Andrea Poli 2008–2009
- Pedro Obiang 2019–2025
- Jeremy Toljan 2019–2021, 2021–2025
- Alfred Duncan 2015–2016, 2016–2020
- Saphir Taïder 2014–2015
- Marash Kumbulla 2024
- Nicola Sansone 2014–2016
- Marcus Pedersen 2023–2024
- Richmond Boakye 2011–2013
- Marco Andreolli 2008–2009
- Andy Selva 2006–2009
- Tarik Muharemović 2024–2025, 2025–2026
- Federico Peluso 2014–2022
Source: Wikidata (CC0), Wikipedia club articles and player infoboxes (years at each club). Youth spells and appearances that look unplayed are left out; volunteer-kept records can contain gaps or errors.