Bundesliga
- Bayern München 25 shared
- Borussia Dortmund 21 shared
- Schalke 04 21 shared
- Eintracht Frankfurt 20 shared
- Roma 10 shared
- Real Madrid 9 shared
- Liverpool 8 shared
- Beşiktaş 7 shared
- Juventus 7 shared
- Paris Saint-Germain 6 shared
- Arsenal 5 shared
- Inter 5 shared
- Monaco 5 shared
- Atlético Madrid 4 shared
- Barcelona 4 shared
- Galatasaray 4 shared
- Manchester City 4 shared
- Aston Villa 4 shared
- Chelsea 4 shared
- Köln 38 shared
- Fortuna Düsseldorf 37 shared
- Nürnberg 30 shared
- VfL Bochum 30 shared
- Hertha BSC 26 shared
- Hamburger SV 25 shared
- Borussia Mönchengladbach 21 shared
- Mainz 21 shared
- Hannover 96 21 shared
- Stuttgart 21 shared
- Arminia Bielefeld 18 shared
- Werder Bremen 18 shared
- Wolfsburg 17 shared
- Augsburg 13 shared
- Greuther Fürth 12 shared
- Union Berlin 12 shared
- Hoffenheim 11 shared
- PSV 10 shared
- Freiburg 9 shared
- RB Leipzig 8 shared
- St. Pauli 7 shared
- Paderborn 7 shared
- Holstein Kiel 7 shared
- Elversberg 6 shared
- Ajax 6 shared
- Olympiakos 6 shared
- Fulham 6 shared
- Eintracht Braunschweig 5 shared
- Darmstadt 98 5 shared
- Strasbourg 5 shared
- Samsunspor 4 shared
- Feyenoord 4 shared
- Rennes 4 shared
- Sunderland 4 shared
- Benfica 4 shared
- Gençlerbirliği 4 shared
- Eskişehirspor 4 shared
- Ankaragücü 4 shared
- Ingolstadt 4 shared
- Kasımpaşa 4 shared
Famous players who played for Bayer Leverkusen
- Heung-min Son 2013–2015
- André Schürrle 2011–2013
- Chicharito 2015–2017
- Kai Havertz 2016–2020
- Daniel Carvajal 2012–2013
- Toni Kroos 2009–2010
- Michael Ballack 1999–2002, 2010–2012
- Arturo Vidal 2007–2011
- Patrik Schick 2020–
- Lucas Vázquez 2025–
- Florian Wirtz 2020–2025
- Hajime Hosogai 2011–2013
- Andrés Guardado 2014
- Arkadiusz Milik 2013–2015
- Julian Brandt 2014, 2014–2019
- Sardar Azmoun 2022–2024
- Jonathan Tah 2015–2025
- Granit Xhaka 2023–2025
- Hakan Çalhanoğlu 2014–2017
- Emre Can 2013–2014
- Bernd Leno 2011, 2012–2018
- Sami Hyypiä 2009–2011
- Dimitar Berbatov 2001, 2001–2006
- Aggelos Charisteas 2009
- Emerson 1997–2000
- Rudi Völler 1994–1996
- Jorginho 1989–1992
- Domagoj Vida 2010–2011
- Landon Donovan 2000–2005
- Niko Kovač 1996–1999
- Lúcio 2001–2004
- Vedran Ćorluka 2012
- Piero Hincapié 2021–2026
- Admir Mehmedi 2015–2018
- Tin Jedvaj 2014–2015, 2015–2021
- Eren Derdiyok 2009–2012, 2013–2014
- Christoph Kramer 2011–2016
- Alejandro Grimaldo 2023–2026
- Emir Spahić 2013–2015
- Sven Bender 2017–2021
Source: Wikidata (CC0), Wikipedia club articles and player infoboxes (years at each club). Youth spells and appearances that look unplayed are left out; volunteer-kept records can contain gaps or errors.